Some people like to keep skunks as pets. There are even genetic lines of skunks with brown and white fur that are raised for pets so as not to be confused with wild skunks. Wild skunks are either illegal to keep as pets or professionally discouraged as pets because of their strong association with rabies.
Skunks can apparently be carriers of rabies without showing any symptoms themselves and without dying from the disease for quite some time... so quarantining a skunk for 10 days does not guarantee that the skunk is not carrying rabies virus.
At any rate, for the few people that keep pet skunks, or for zoos, some vets will surgically remove the scent glands. I've done a few of these in the past but refuse to do anymore. Just one drop of skunk juice in the hospital will put me out of business for a week. And just because a young skunk is used to being held and petted by humans doesn't mean it isn't going to freak in a hospital full of barking dogs and a human with a syringe in his hand.
If you have a skunk that needs to be descented, expect your vet to cut a few corners and perform the surgery outside the clinic...probably at your place.
Ferrets: The one reference I found on this subject considered it mutilation to descent a ferret. I've never done this surgery and don't know much about the topic
On This Page:
Surgery; a very few comments about descenting ... something I don't know much about
Cardiology Heart disease in Cats, Cardiac Hypertrophy, Valvular disease, Cardiac Insufficiency, Congestive Heart Failure, Heartworm Disease, and a little history about the milestones in treating heart disease
Cats: general information page and directory of diseases and problems specific to cats including vaccine recommendations, leukemia, feline viral infections, feline upper respiratory disease and cats that just aren't feeling well.